THERASAM

Localized radiotherapy, using Holmium with purpose and precision

Ghost: An innovative Holmium-Based Platform

Ghost by TheraSAM is a holmium-based radiotherapeutic of neutron irradiated microspheres that delivers precise, localized beta and gamma radiation to solid tumors.

LOW-COST HOLMIUM

Rare earth element.
Short activation time (1h).
Quick radioactive decay (26h).
Magnetic properties.

GLASS

Resistance to melting.
Structural and thermal stability.
Low radiation activation.
Higher radioactive loading vs PLLA — improving logistics window and clinical effectiveness.

Ghost microspheres are developed by gluing holmium on the surface of glass microspheres

A value proposition meeting the needs of patients HCPs, and HC
system

TheraSAM offers significant value to patients, doctors, and hospitals & clinics, while enhancing patient outcomes for both candidates and non-candidates for radio-chemo-immunotherapy.

1

For Patients

Receive a highly targeted, minimally invasive treatment that increases survival rate,
reduces recurrence and side effects, enabling faster recovery and fewer complications compared to systemic therapies.

2

For Healthcare Professionals

Benefit from a safe, efficient, and precise loco-regional radiotherapy system that integrates easily with existing clinical workflows and allows for fully personalized cancer treatment, with no need for side-effects management.

3

For Hospital & Clinics

Achieve lower hospitalization and radiotherapy-related costs, improve infrastructure compatibility, and reduce overall treatment expenses without requiring major investments, reshaping the overall investment model toward a patient-based approach.

TheraSAM leading the way in precision loco-regional radiotherapy

Empowering oncology through precision loco-regional radiotherapeutics, TheraSAM develops innovative, holmium-based solutions to deliver highly localized and effective cancer treatments, minimizing side effects and maximizing clinical impact.

Why We Joined Forces

We bring together leading experts in nuclear physics, radiopharmacy, and surgical oncology. Driven by a shared belief in the untapped potential of holmium, we united to pioneer a new class of precision radiotherapeutics that bridge the gap between effectiveness and accessibility, from hospitals to outpatient settings.

Focus Area & Future Outlook

Our current focus is on oncology applications, with a primary target on medical-grade devices for loco-regional treatment. Given holmium’s unique characteristics and our capabilities, future expansion into other therapeutic areas or industries remains a strategic opportunity to leverage.

TEAM

Strong Scientific Team with 100+ years of experience in Oncology and Nuclear Science

Stephane Chauvie

Co-Founder

Medical Physicist with 30+ years of experience in oncology imaging, radioprotection, and clinical trial coordination.

Achille Cester

Co-Founder

Experienced engineer with 30+ years of expertise in radiation protection, industrial safety and risk management, and pressure equipment.

Maurizio Grosso

Co-Founder

Interventional Radiologist with 40+ years of clinical and academic experience, also leading specialized departments.

Daniela Santarelli

Acting CEO

Pharma Industry Leader with 25+ experience in Commercial,&
Access Strategy and Launch Excellence.

ADVISORY BOARD

Felice Borghi

Director of Oncologic Surgery at the Candiolo Cancer Institute.

Marcus Scaramanga

Co-Founder of Minnex & Nest Hotels, with a degree in Mechanical Engineering from the University of Bristol.

Lucrezia Cester

Ph.D. in Biomedical Imaging from the University of Glasgow, Founder of LightHearted AI, Forbes 30 Under 30.

Massimo Oddone

Radiochemist and Associate Professor of General Chemistry at the University of Pavia.

TheraSAM’s Unique Edge

  • HOLMIUM-BASED MULTI-APPLICABILITY PLATFORM
  • OPERATIONAL EXCELLENCE & MODEL READINESS
  • WORLD-CLASS, CROSS-FUNCTIONAL TEAM
  • SUSTAINABILITY AS A STRATEGIC LEVER
  • MARKET WITH HIGH POTENTIAL

Precision and innovation in localized radiotherapy

info@therasamsrl.com

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